Polynucleotides

Real Results

Before & After

Before & After
Before & After
Before & After
Before & After
Before & After
Before & After

“Absolutely incredible results”

Amazing service and amazing results. Roger is clearly an expert at what he does. I felt completely at ease throughout and the results exceeded all my expectations.

Shelly

Shelly

Polynucleotides · Verified Client

“Professional from start to finish”

Absolute professional. I couldn't be happier with my experience at XO Clinic. From the consultation to the aftercare, everything was handled with genuine care.

Andrew

Andrew

Polynucleotides · Verified Client

“The most welcoming clinic”

The most welcoming clinic I've ever visited. Highly recommend to anyone looking for top-quality aesthetic treatments. Roger is exceptional at what he does.

Emma

Emma

Polynucleotides · Verified Client

“Absolutely incredible results”

Amazing service and amazing results. Roger is clearly an expert at what he does. I felt completely at ease throughout and the results exceeded all my expectations.

Shelly

Shelly

Polynucleotides · Verified Client

“Professional from start to finish”

Absolute professional. I couldn't be happier with my experience at XO Clinic. From the consultation to the aftercare, everything was handled with genuine care.

Andrew

Andrew

Polynucleotides · Verified Client

“The most welcoming clinic”

The most welcoming clinic I've ever visited. Highly recommend to anyone looking for top-quality aesthetic treatments. Roger is exceptional at what he does.

Emma

Emma

Polynucleotides · Verified Client

Individual results may vary. All photos shown with client consent.

XO Clinic

About This Treatment

PDRN/PN salmon DNA injections for regeneration, repair, rejuvenation. Under-eye hollows, fine lines.

All treatments at XO Clinic are carried out by award-winning practitioner Roger Compton, ensuring the highest standards of safety, precision, and clinical excellence. Your consultation is always included, and full aftercare guidance is provided to support your results.

500+ FIVE-STAR REVIEWS
FREE CONSULTATION
NO UPFRONT PAYMENTS

Key Benefits

  • PDRN/PN for cellular regeneration
  • Excellent for under-eye hollows & dark circles
  • Reduces fine lines and improves skin quality
  • Stimulates tissue repair and hydration
  • Safe, biocompatible treatment

Starting From

from £240

Includes FREE consultation

Book Now

*Free consultation · No upfront payments

COMMON QUESTIONS

Frequently Asked Questions

Polynucleotides are highly purified chains of DNA that stimulate tissue regeneration, improve skin hydration, reduce inflammation, and promote new cell growth. They are among the most advanced skin rejuvenation treatments currently available.

At XO Clinic in Wakefield, polynucleotides are used to treat under-eye hollows, dark circles, fine lines, skin laxity, and overall skin quality. They are also highly effective for hair restoration in cases of thinning hair.

A typical course is 2–3 sessions, spaced 3–4 weeks apart. Maintenance is usually recommended every 6 months. Results improve progressively over the course of treatment as skin regeneration takes effect.

Polynucleotides are biocompatible and biodegradable, making them extremely safe with an excellent tolerability profile. All treatments at XO Clinic are administered by Roger Compton, an award-winning pharmacist independent prescriber with over 10 years of experience.

XO Clinic offers polynucleotide treatments at our Wakefield clinic, with a second location opening in Leeds. We're proud to bring the latest regenerative skin science to clients across West Yorkshire, administered by a clinician with over a decade of specialist experience.